Welcome to the HPRC Blog. We've got lots of information here, from quick tips to in-depth posts about detailed human performance optimization topics.
HPRC Fitness Arena: Dietary Supplements
Some dietary supplements marketed for weight loss contain “raspberry ketone.” This ingredient is one of several naturally occurring chemicals found in red raspberries that contribute to their aroma; it also occurs in other fruits such as cranberries and blackberries. Raspberry ketone is used in some foods as a flavoring agent and in other products such as cosmetics. Because the amount of raspberry ketone found naturally is so low, it is produced synthetically in a laboratory for use in commercial products.
The limited number of studies done on cells, mice, rats, and other small animals indicate that raspberry ketone might improve fat metabolism. However, the same effect has yet to be established in humans, and currently there is insufficient scientific evidence that supplemental raspberry ketone is effective for weight loss.
Is your New Year’s resolution to try to lose weight, meet body composition standards, or just be healthier? Weight-loss supplement might be a tempting solution, but before you take one, consider this: Dietary supplements marketed for weight loss are categorized “high-risk” products. The Food and Drug Administration has found many dietary supplement products marketed for weight loss to contain hidden drug ingredients or other ingredients that haven’t been adequately studied in humans.
Not only are they potentially unsafe, weight-loss supplements that advertise “quick fixes” likely won’t help you meet your goals. There’s limited scientific evidence that weight-loss supplements alone help people lose a significant amount of weight and keep it off. Question the claims on the label, and remember: If it sounds too good to be true, it probably is.
Phenibut—also “β-phenyl-γ-aminobutyric acid” or “4-amino-3-phenylbutyric acid HCl”—is found as an ingredient in some dietary supplements. These supplements are sold for a variety of uses, including sleep, stress reduction, and nootropic (“smart pill”) effects. Phenibut is a drug developed in Russia and Latvia, where it’s used as to treat anxiety, alcohol withdrawal, insomnia, and other conditions.
In the U.S., phenibut is neither a controlled substance nor a prescription drug. But that doesn’t mean it’s “okay.” Phenibut is a synthetic substance—it’s made in a laboratory and doesn’t occur in nature—which means it doesn’t fit FDA’s definition of an acceptable dietary supplement ingredient. It’s similar to the FDA-approved drug baclofen.
There are reports of adverse events associated with phenibut use, and some evidence suggests that continued use can lead to dependence and increased tolerance, which means an increasingly higher dose is needed for the same effect. Withdrawal symptoms include visual and auditory hallucinations, muscle pain and twitching, heart arrhythmia (tachycardia), nausea, vomiting, insomnia, sensitivity to sound and light, and separation from reality.
Although FDA has not yet declared phenibut illegal for use in dietary supplements, we advise caution.
Energy drinks can actually pose health risks to adolescents, yet approximately 30% of teens consume them on a regular basis. The risks include increased heart rate, high blood pressure, anxiety, digestive problems, sleep disturbances, dehydration, and even death. In addition, teens who consume energy drinks are also more likely to engage in unhealthy behaviors such as drinking more sugar-sweetened beverages, smoking cigarettes, and using drugs and alcohol.
Many of the negative effects associated with energy drinks are due to the large amounts of stimulants in these beverages. Their caffeine content can range from 50 to more than 300 mg per can or bottle. However, the amount of caffeine teens consume from energy drinks is trending upwards, in part due to heavy marketing with celebrity athletes.
The American Academy of Pediatrics recommends that children and teens consume no more than 100 mg of caffeine per day (equal to about 2 cans of caffeine-containing soda or one 8 oz. cup of coffee) and avoid energy drinks altogether. They provide no nutritional benefit.
Parents: Be sure to talk to your teens about the potential problems associated with energy drinks, and make sure they don’t confuse them with sports drinks, which teens should use only when needed.
Some dietary supplements are marketed as “all natural,” but do you know that this is actually an unregulated marketing term? So just because a product claims to be “all natural” doesn’t automatically make it safe. In fact, the Food and Drug Administration (FDA) warns that products marketed as “all natural” might contain ingredients that could interact with medications or be harmful to people with certain medical conditions or may even contain hidden drug ingredients. For example, according to FDA, supplements marketed as “all natural” sexual-enhancement products might be tainted with the same active ingredients found in prescription drugs used to treat erectile dysfunction. Not only could you potentially be consuming multiple drug ingredients, you could be consuming them in amounts even greater than prescription doses. Either way, these types of products can put your health and career in danger. For more information, please read FDA’s “Consumer Update on 'All Natural’ Alternatives…”
You can’t always believe the marketing claims, advertisements, or even labels of dietary supplement products. That’s because the Food and Drug Administration (FDA) doesn’t approve or evaluate supplements for safety, quality, or effectiveness before they are sold on the market. FDA can, however, take action if a product is later found to be adulterated or misbranded or cause harm. Still, sometimes it can be hard to tell which supplements are safe and which you should leave on the shelf. To learn more, take a few minutes to watch this video from Operation Supplement Safety about Decoding the Dietary Supplement Industry.
Garcinia cambogia, a pumpkin-like fruit, is a popular dietary supplement ingredient in products marketed for weight loss. Although Garcinia cambogia has been marketed as a weight-loss aid for quite some time, the latest scientific research still hasn’t proven its effectiveness. To learn more, read the updated Operation Supplement Safety (OPSS) FAQ about Garcinia cambogia.
If you’re looking for ways to lose weight, OPSS and HPRC always recommend choosing foods first before considering dietary supplements. Visit HPRC’s Fighting Weight Strategies, where you’ll find joint-service and service-specific programs to help you achieve your goals.
Creatine supplements are popular among athletes and Warfighters trying to enhance their strength and muscle size. Unlike many other supplements, there is considerable evidence that taking creatine supplements might result in greater gains in body mass and strength when combined with resistance training. However, not all athletes or Warfighters will experience the same benefits from consuming creatine supplements, especially those focused on endurance training. And although there are few safety concerns associated with creatine, it’s still important to use it under the guidance of a healthcare provider. Read more...
Green coffee bean extract has been available in dietary supplements for quite some time, but despite the hype and popularity of this ingredient, there’s little science to support its use as a weight-loss aid. Green coffee beans are the raw, unroasted seeds or “beans” of the Coffea plant. Similar to your morning cup of coffee, they contain caffeine in addition to a chemical called chlorogenic acid. The difference, though, is that green coffee beans contain more chlorogenic acid because roasting reduces the amount of chlorogenic acid in coffee beans.
Chlorogenic acid supposedly offers some health benefits, but don’t believe everything you hear (or read) about green coffee beans supplements for weight loss; there just isn’t enough evidence to back up these claims. In fact, the Federal Trade Commission (FTC) charged a company for using deceptive weight-loss claims to market a green coffee bean supplement. Read more about this in FTC’s Press Release.
Dietary supplements and medications (prescription or over-the-counter) can be a risky combination. That’s because many dietary supplement ingredients, especially herbs and botanicals, can interact with drugs (such as ones to treat blood pressure, diabetes, depression, and anxiety) or even other dietary supplements. Interactions between drugs and supplements can result in either an increase or decrease in the effectiveness of your medications. In other words, you could be getting too much or too little of the medications that you need, which can be dangerous to your health. If you’re taking or plan to take a dietary supplement, inform your healthcare provider to make sure it’s safe to use with your medications.
Learn more about how supplements can change the effectiveness of your medications and know when drug-supplement interactions are especially important by using this interactive web resource from the National Center for Complementary and Integrative Health (NCCIH). And for information about many known interactions between dietary supplement ingredients and medications, as well as other dietary supplement ingredients, visit the Natural Medicines Comprehensive Database (NMCD).