Filed under: OPSS
The Consortium for Health and Military Performance (CHAMP) hosted a workshop last week (July 21, 2016) on appearance- and performance-enhancing substances. Subject-matter experts from Harvard University, the University of Missouri, and the Department of Defense spoke about androgenic anabolic steroids (AAS) and how the use of AAS has emerged as a major public-health problem, particularly among young male weightlifters. The exact number of military members using AAS is not known, but there is known use, and it might be higher than expected. The panel discussed the impact of AAS on military readiness—potential risks and potential benefits—and the need for more research in this area.
The National Institute on Drug Abuse has some good resources on AAS, particularly their short- and long-term effects. And for information about other performance-enhancing substances, please visit Operation Supplement Safety (OPSS).
Aconitum kusnezoffii—one of several plants known as aconite—is being marketed in some dietary supplement products as a source of the stimulant 2-aminoisoheptane. All aconites naturally contain a toxin called “aconitine” and are considered poisonous. Although some types of aconite are used in traditional Chinese medicines, the plant must be properly processed, or it can be dangerous and lethal. Even when properly processed, it can still be dangerous.
There is no scientific evidence that 2-aminoisoheptane, also called octodrine or DMHA, occurs in aconite or anywhere else in nature. Octodrine is a nasal decongestant, first made in a laboratory in 1944. Without laboratory testing, there’s no way to know if a dietary supplement product labeled with this ingredient contains 2-aminoisoheptane or aconite (or both) or any of the other toxic chemicals found in aconite. Bottom line: If a product lists “2-aminoisoheptane (Aconitum kusnezoffii)” as an ingredient, it could be problematic.
Since May 2016, 43 dietary supplement products have been added to the Operation Supplement Safety (OPSS) High-Risk Supplement List, bringing the total number of products on the list to 247. Together with the U.S. Anti-Doping Agency (USADA), OPSS frequently updates the list to help you stay informed about current high-risk products. You can access the High-Risk Supplement List from the OPSS web page or download the app (from the Apps tab) to your phone or tablet and take it wherever you go. If you’re considering dietary supplements, be sure to check back often for more updates.
Picamilon goes by many names, such as pikatropin and nicotinyl-gamma-aminobutric acid, but one thing it can’t be called is a dietary ingredient. In 2015, the Food and Drug Administration declared that picamilon is not a legal ingredient in dietary supplements and sent warning letters to 5 companies whose dietary supplement products contained picamilon. So why is it illegal? Find out in the Operation Supplement Safety (OPSS) FAQ about picamilon.
If you want to learn more about other questionable ingredients, explore the OPSS FAQs about dietary supplement ingredients.
In recent years, the Food and Drug Administration (FDA) has taken action against dietary supplement companies for selling products with ingredients that put them in a category of being “adulterated” or “misbranded.” Examples of these ingredients include Acacia rigidula, BMPEA, DMAA, DMBA, ephedra, methylsynephrine, and picamilon. Such ingredients have been determined to be unsafe, lack evidence of safety, don’t meet the definition of a dietary ingredient, or combinations of these issues. Some are even used as drugs in other countries.
Although these ingredients are not allowed in dietary supplements, you might still find them in some products, so always read product labels carefully. Service members especially take note! Since FDA has declared the ingredients listed above (and others) to be “illegal” or “not allowed” in dietary supplements for one reason or another, commands have restricted their use by military members. For more information about FDA’s role in regulating dietary supplement products and ingredients, visit FDA’s web page.
DHEA, short for dehydroepiandrosterone (also known as Prasterone), and chemical variations of this dietary supplement ingredient are commonly found in products marketed for sexual enhancement and bodybuilding such as testosterone boosters and prohormones. They’re also marketed to produce effects similar to anabolic steroids. Unlike anabolic steroids, DHEA is not illegal, but it is prohibited by professional sports organizations such as the World Anti-Doping Agency (WADA) and the National Collegiate Athletic Association (NCAA). Members of the Coast Guard should especially look out for supplements containing this ingredient, as they are not permitted to take any substances NCAA classifies as anabolic agents. To learn more, visit the OPSS FAQ about DHEA.
Operation Supplement Safety (OPSS) has a new infographic about stimulants. Do you want to know what types of dietary supplements commonly contain stimulants? Or how to tell if your supplement contains a stimulant? Or what can happen if you take too much or too many stimulants? Get up to speed and check out the infographic below with information on what you need to know about these dietary supplement ingredients. Use it in conjunction with the OPSS stimulants list to help you with these ingredients often found in dietary supplements.
Another ingredient that has been showing up in dietary supplement products recently is Acadia rigidula. FDA recently declared that it is not acceptable in such products because it falls in the class known as a “new dietary ingredient.” A. rigidula is just the latest in a series of ingredients FDA has disallowed for this reason. Others include DMAA, DMBA, BMPEA, and aegeline. Visit the Operation Supplement Safety (OPSS) FAQ about Acacia rigidula to learn more, and explore the OPSS FAQs about ingredients to learn about others not permitted in dietary supplement products. especially BMPEA, which has been associated with A. rigidula.
If you’ve searched recently for dietary supplements to enhance your performance, you may have come across products marketed as “ketone supplements.” Before you consider taking any of these products, read the new Operation Supplement Safety FAQ about ketone supplements. Learn what ketone supplements are and if they’re worth the often-hefty price tag.
If you’re curious about other supplements marketed for performance, check out the OPSS Performance FAQs. Can’t find the answers you’re looking for? Send us a question using our Ask the Expert feature.
In the sea of dietary supplements, can you tell which ones are safe to take and which to avoid? Do you often find yourself confused, wondering what you should be looking for in a product? Operation Supplement Safety (OPSS) has you covered. Here are just some of the tools that OPSS provides to help you choose supplements wisely:
- Frequently Asked Questions (FAQs). HPRC receives hundreds of questions every year, and we’ve put answers to the most frequently asked questions in this section of OPSS. You’ll find information about banned substances in the military, hot-topic dietary supplement ingredients, and more.
- OPSS Scorecard. The scorecard consists of just 7 questions to show you what to look for on a product label and help you determine if a product is okay or a “no-go.”
- OPSS High-Risk Supplement List. With HRSL, you can see if a certain dietary supplement product might pose a health or sport anti-doping risk.
- Natural Medicines Comprehensive Database. NMCD, a partner of HPRC, provides information about the safety and effectiveness of thousands of dietary supplement products and ingredients. And best of all, it’s free to all DoD personnel with a “.mil” email address.
The goal of OPSS is to provide you with the most reliable and relevant information about dietary supplements, but if you can’t find what you’re looking for, send us a question using our Ask the Expert feature.