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What are high-risk supplements?

HPRC Fitness Arena: Dietary Supplements
Some dietary supplement products contain problematic ingredients. Find out which ones might pose a health risk.

High-risk dietary supplements are those that may present serious health risks. Many have been found to contain undeclared drug ingredients, steroids, steroid-like ingredients, and/or stimulants, which can have negative and dangerous side effects. Products most commonly “tainted” in this way are those marketed for bodybuilding, performance enhancement, weight loss, sexual enhancement, and diabetes. Such products may also result in a positive drug test. For more information, read FDA’s Consumer Update “Tainted Products Marketed as Dietary Supplements.” For more information about urinalysis and drug testing, read HPRC’sDietary supplements and drug testing."

In addition, you can visit the OPSS High-Risk Supplement List for information about certain dietary supplements that may pose a health or sport anti-doping risk.

For more Frequently Asked Questions about dietary supplements, visit the Operation Supplement Safety (OPSS) FAQs.

Download the OPSS app

Use the Operation Supplement Safety & Natural Data app to get information and safety ratings on commercially available dietary supplement products and ingredients.

Operation Supplement Safety (OPSS) is a joint military initiative between the Human Performance Resource Center (HPRC) and the Department of Defense (DoD) to educate service members and retirees, their family members, leaders, healthcare providers, and DoD clinicians about dietary supplements and how to choose them wisely.

OPSS has partnered with Natural Medicines Comprehensive Database (NMCD) to provide all DoD personnel with access to evidence-based information on dietary supplements, including Natural Medicines Brand Evidence-based Ratings (NMBER)®.

Now there is an Operation Supplement Safety & Natural Data (OPSS & ND) app available that can help you make an informed decision by giving you:

  • Dietary supplement safety and effectiveness (NMBER) ratings.
  • Interaction ratings between drugs and natural medicines, known as “adverse reactions.”
  • Effectiveness ratings for natural medicines by medical condition and more.

To access the app you must first visit HPRC’s link to NMCD and sign up for your free account. Click on the Warfighter version and use your valid .mil email address. Once you’ve created your free account you will have access to the full version of the app. Up-to-date reviews of commercially available products, Natural Medicines Brand Evidence-based Ratings (NMBER)® for commercially available products, an Effectiveness Checker, and more will be at your fingertips.

The OPSS & ND app is available at these links for Android and for iPhone/iPad, or go to the Google or iTunes stores and search for “Operation Supplement Safety.”

If you have questions, please use the “Ask the Expert” button on the OPSS home page.

Can you spot a red flag?

Choose supplements safely. Learn how to spot red flags.

When something sounds too good to be true, it probably is. Dietary supplements are popular among military personnel, and it’s important to be able to spot the red flags—warning signs of potential problems—when considering a product. Read the OPSS FAQ on how to spot these red flags to help make an informed decision. And be sure to check back often for new FAQs.

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