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Filed under: Supplements

What’s the deal with DHEA?

Filed under: OPSS, Supplements
DHEA is a hormone and marketed to have anabolic effects. Does this make it illegal?

DHEA, short for dehydroepiandrosterone (also known as Prasterone), and chemical variations of this dietary supplement ingredient are commonly found in products marketed for sexual enhancement and bodybuilding such as testosterone boosters and prohormones. They’re also marketed to produce effects similar to anabolic steroids. Unlike anabolic steroids, DHEA is not illegal, but it is prohibited by professional sports organizations such as the World Anti-Doping Agency (WADA) and the National Collegiate Athletic Association (NCAA). Members of the Coast Guard should especially look out for supplements containing this ingredient, as they are not permitted to take any substances NCAA classifies as anabolic agents. To learn more, visit the OPSS FAQ about DHEA.

Stimulants – Are you up to speed?

Check out the new OPSS infographic about stimulants!

Operation Supplement Safety (OPSS) has a new infographic about stimulants. Do you want to know what types of dietary supplements commonly contain stimulants? Or how to tell if your supplement contains a stimulant? Or what can happen if you take too much or too many stimulants? Get up to speed and check out the infographic below with information on what you need to know about these dietary supplement ingredients. Use it in conjunction with the OPSS stimulants list to help you with these ingredients often found in dietary supplements.

Full Image of the Stimulants PDF

Acacia rigidula: another FDA target

Dietary supplement products containing Acadia rigidula are not allowed.

Another ingredient that has been showing up in dietary supplement products recently is Acadia rigidula. FDA recently declared that it is not acceptable in such products because it falls in the class known as a “new dietary ingredient.” A. rigidula is just the latest in a series of ingredients FDA has disallowed for this reason. Others include DMAA, DMBA, BMPEA, and aegeline. Visit the Operation Supplement Safety (OPSS) FAQ about Acacia rigidula to learn more, and explore the OPSS FAQs about ingredients to learn about others not permitted in dietary supplement products. especially BMPEA, which has been associated with A. rigidula.

Ketone supplements

Are ketone supplements the key to improving your performance?

If you’ve searched recently for dietary supplements to enhance your performance, you may have come across products marketed as “ketone supplements.” Before you consider taking any of these products, read the new Operation Supplement Safety FAQ about ketone supplements. Learn what ketone supplements are and if they’re worth the often-hefty price tag.

If you’re curious about other supplements marketed for performance, check out the OPSS Performance FAQs. Can’t find the answers you’re looking for? Send us a question using our Ask the Expert feature.

FDA says no to methylsynephrine

FDA has declared that methylsynephrine can’t be used in dietary supplements. Be sure to check your product label.

The Food and Drug Administration recently announced that methylsynephrine (also known as oxilofrine) “does not meet the statutory definition of a dietary supplement ingredient.” So what does this mean? Products containing methylsynephrine are adulterated and can’t be marketed legally as dietary supplements. Methylsynephrine is also prohibited in sport because it’s a pharmaceutical drug (not currently approved in the U.S) and a stimulant that increases blood pressure and affects heart rate. What’s more, some supplements have been found to contain methylsynephrine in amounts equal to or greater than pharmaceutical doses.

The consequences of taking methylsynephrine in large amounts or in combination with other stimulants aren’t entirely known, but one product containing this ingredient and other stimulants has been linked to nausea, vomiting, agitation, increased heart rate, chest pain, and cardiac arrest. If you’re considering taking a dietary supplement with methylsynephrine or oxilofrine on the label, you might want to think twice. For more from FDA, please see “Methylsynephrine in Dietary Supplements.”

Supplement safety for teen athletes

Filed under: Supplements, Teens
The science doesn’t support the use of supplements by teens. What can you do to keep them safe?

Most dietary supplement products are marketed for adults 18 and older and typically carry a warning on the label against use by those under 18. That’s because there has been little to no reliable research done on the use of dietary supplements—especially those marketed for bodybuilding and performance enhancement—by people under the age of 18. As such, the National Federation of State High School Associations (NFHS) strongly opposes the use of dietary supplements by high school athletes to gain a competitive advantage.

Whether you’re a teen athlete, parent, coach, or healthcare provider, here are a few things to keep in mind:

Teens: Achieving your athletic goals means hard work. Taking shortcuts with dietary supplements can be harmful to your health and have a negative effect on your future athletic ambitions. Watch OPSS’s video below to learn about one college athlete’s experience.

Parents and coaches: Talk often with your athletes about dietary supplements, and encourage them to eat whole foods to fuel their bodies. Download HPRC’s “Fueling the adolescent athlete,” which has helpful suggestions for hydrating and for eating between workouts.

Healthcare providers: Use the OPSS Guidelines to ask about supplement use as part of taking a comprehensive dietary supplement history. Counsel athletes and their parents about the risks involved with using dietary supplements and other performance-enhancing substances. Promote proper nutrition, training, and rest to improve performance.

Remember, teens (and adults) can get all the nutrients their bodies need by eating a variety of nutrient-rich foods. Teens and adults don’t need supplements unless a doctor determines it’s needed to treat deficiency of a particular nutrient.

SARMs don’t cut it

SARMs are unapproved drugs that keep popping up in dietary supplement products.

SARMs (selective androgen receptor modulators) are unapproved, experimental drugs sometimes illegally marketed and sold as dietary supplement products. They’re also available on the Internet in other forms, but their use in sport is prohibited. Use of SARMs can affect military performance and readiness.

Operation Supplement Safety (OPSS) has an FAQ about SARMS, including a link to a list of more than 200 dietary supplements and other commercial products containing SARMs. The list also includes an extensive list of SARM names to help you identify them on product labels.

HPRC’s Ask the Expert feature is available if you have particular questions about these ingredients or any other questions about dietary supplements.

What’s in your supplement safety tool belt?

Filed under: OPSS, Supplements
Not all supplements are dangerous, but are you equipped with the tools to help you determine which ones are?

In the sea of dietary supplements, can you tell which ones are safe to take and which to avoid? Do you often find yourself confused, wondering what you should be looking for in a product? Operation Supplement Safety (OPSS) has you covered. Here are just some of the tools that OPSS provides to help you choose supplements wisely:

  • Frequently Asked Questions (FAQs). HPRC receives hundreds of questions every year, and we’ve put answers to the most frequently asked questions in this section of OPSS. You’ll find information about banned substances in the military, hot-topic dietary supplement ingredients, and more.
  • OPSS Scorecard. The scorecard consists of just 7 questions to show you what to look for on a product label and help you determine if a product is okay or a “no-go.”
  • OPSS High-Risk Supplement List. With HRSL, you can see if a certain dietary supplement product might pose a health or sport anti-doping risk.
  • Natural Medicines Comprehensive Database. NMCD, a partner of HPRC, provides information about the safety and effectiveness of thousands of dietary supplement products and ingredients. And best of all, it’s free to all DoD personnel with a “.mil” email address.

The goal of OPSS is to provide you with the most reliable and relevant information about dietary supplements, but if you can’t find what you’re looking for, send us a question using our Ask the Expert feature.

Imported supplement scams

Filed under: OPSS, Supplements
Products labeled as “natural” aren’t always what they seem.

If you buy dietary supplements at international stores, gas stations, or online, watch out. The Food and Drug Administration (FDA) warns consumers about imported dietary supplements and nonprescription drug products, specifically those marketed as “natural.” Just because a product is labeled as “natural” does not necessarily make it safe or effective. In fact, many “natural” products have been found to contain undisclosed chemicals or drugs that can be harmful, and it’s possible that some products contain hidden ingredients that could make you pop hot on a drug test. To learn more, please read FDA’s “Some Imported Dietary Supplements…” Only have a minute? Watch their 60-second video below.

The only way to know if a product actually contains the ingredients listed on the label (and nothing else) is by testing it in a laboratory. Before you buy a dietary supplement, check the label to see if it’s been tested by a third-party organization.

Nootropics on your mind?

If you’re looking for cognitive enhancers or “smart drugs,” you may want to think twice.

Many dietary supplement products are marketed as nootropics—substances intended to improve memory, focus, and overall mental performance. While some products contain vitamins, minerals, and plant-based ingredients, others contain drugs that are not legal dietary supplement ingredients. Read the Operation Supplement Safety (OPSS) FAQ about nootropics to learn more about these products and whether they are safe and effective.

Not all ingredients found in dietary supplements are legal, so read product labels carefully. For more information, visit FDA’s Dietary Supplement Products & Ingredients.

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