Filed under: Supplements
The Food and Drug Administration (FDA) is warning consumers about powdered pure caffeine, particularly as sold in bulk on the Internet. At least one death has been associated with the use of such products, and FDA advises consumers about the potency of powdered pure caffeine. See FDA’s Consumer Advice, which includes information about how to report an adverse event.
According to this consumer resource from FDA, you should limit your caffeine intake to just 100–200 mg per day (about 5–10 ounces of coffee). Taking large doses of caffeine—roughly 400–500 mg—at one time can result in a serious condition known as “caffeine intoxication.” Some symptoms of caffeine intoxication are minor and include nausea, vomiting, agitation, nervousness, or headache. Other symptoms can be more life-threatening, such as rapid heartbeat, electrolyte imbalance, very high blood sugar, or high levels of acid in the blood, which can cause seizures. See the OPSS FAQ to help you avoid hidden sources of caffeine.
HPRC has written several articles about energy drinks, their ingredients, and their potential harmful effects, especially for adolescents. They continue to be the topic of news articles, with another recent death of a teen who apparently consumed several energy drinks while on vacation and then died from cardiac arrest. The American Association of Poison Control Centers (AAPCC) urges the public to use caution when consuming energy drinks and lists many potential harmful reactions. Read more on this AAPCC web page, including statistics on reports of “exposures” to energy drinks.
HPRC has an Infosheet on energy drinks, highlighting the ingredients you may find on labels,and their potential stimulant effects. Be aware of the potential dangers, especially for children and teens, as outlined by the American Academy of Pediatrics.
Garcinia cambogia is being used as a dietary supplement ingredient in some products marketed for weight loss. What is it? And is it effective? Read this Operation Supplement Safety (OPSS) FAQ about Garcinia cambogia to find out. Be sure to check back often, as we add answers to other questions about ingredients in performance and weight-loss supplements and how to choose supplements safely.
If you have more questions about a particular dietary supplement ingredient or product, you can visit the Natural Medicines Comprehensive Database or use our “Ask the Expert” button located on the OPSS home page.
Last summer the Netherlands removed the weight-loss dietary supplement product Dexaprine from the market due to reports of serious adverse events, but the results of research into the cause has just been released. A recent article in Drug Testing and Analysis described at least 26 cases of Dexaprine toxicity reported to the Dutch Poisons Information Center. Testing revealed the existence of “a cocktail of synthetic stimulants” including synephrine, oxilofrine, deternol, yohimbine, caffeine, and theophylline, and possibly ß-methyl-ß-phenylethylamines. (Problematic forms of phenylethylamines, including ß-methylphenylethylamine. were discussed in an April 2014 article in the New England Journal of Medicine.) For more information about tainted weight-loss dietary supplements, see the Food and Drug Administration’s information. Note that this product is still available in the U.S. and online.
When something sounds too good to be true, it probably is. Dietary supplements are popular among military personnel, and it’s important to be able to spot the red flags—warning signs of potential problems—when considering a product. Read the OPSS FAQ on how to spot these red flags to help make an informed decision. And be sure to check back often for new FAQs.
An important part of HPRC’s mission of fostering Warfighter resilience and optimizing Warfighter performance is informing you about the potential hazards associated with dietary supplements. But that’s a two-way street—we need your help too. An April 2014 article in The New England Journal of Medicine points out a major problem: Government agencies don’t get information about adverse effects of dietary supplements quickly enough from the public and healthcare professionals.
HPRC offers an easy way for you to directly report side effects you believe are associated with dietary supplements through the Natural Medicines Comprehensive Database (NMCD). Just go to our NMCD page and click on the icon for Natural Medicines Watch. You don’t even need an NMCD account; it’s free for everyone and easy to use. NMCD will make sure the information reaches FDA’s MedWatch.
Don’t hesitate to report something—you’ll be helping others avoid potentially serious health problems. Not sure about your symptoms? Read HPRC’s article about how to know if you’ve had an adverse event.
March is National Nutrition Month, and it reminds us about the importance of healthy eating. The theme this year is “Enjoy the Taste of Eating Right.” HPRC receives many questions that ask what the best supplements are for weight loss, bodybuilding, and enhancing performance. Our message is always the same: Focus on food first. Operation Supplement Safety (OPSS) has educational resources to help spread this message, including our “Real Food” poster and “Nutrition: Fueled for Fitness” brochure. Be sure to visit OPSS for infosheets, videos, and other educational materials for Warfighters, healthcare providers, and family members.
In a 1960s TV cartoon series, George Jetson of The Jetsons simply popped a pill when he wanted to eat. “Dinner in a pill” was promised as the food of the future. So why hasn’t technology delivered on its promise? Simply put, no dietary supplement can reproduce the aromas, flavors, textures, or nutritional value of oven-roasted turkey, crusty, fresh-baked bread, juicy ripe pineapple, fragrant hot tea, or any other wholesome, delicious, performance-enhancing real food or beverage. And substituting dietary supplements for real food won’t help performance either – check out our video here. So skip supplements—not meals. To learn more about how real foods should come before dietary supplements, check out HPRC’s article in Operation Supplement Safety (OPSS).
Food and health are hot topics these days. Just turn on the TV, pick up a magazine, or glance at the margins of your social networking site and you’ll hear and read about the supposed health benefits of dietary supplements containing this or that food component and the promises that they will “burn belly fat” or some similar claim.
Many of these promising food components belong to a group of compounds referred to as phytochemicals—chemicals produced by plants as a means of protecting the plants from various diseases.
Interestingly, when you eat plants (such as fruits and vegetables), the phytochemicals they contain might protect you from disease too. Researchers have found that people who eat a lot of fruits and vegetables have lower rates of heart disease, cancer, diabetes, and many other diseases. Scientists haven’t discovered exactly how these compounds work to protect us, but they have discovered that they seem to have a synergistic effect. That is, the compounds seem to work better in combination, especially when they are supplied in their natural form—whole foods. Consuming isolated single compounds, as in dietary supplements, rarely has the same beneficial effect as eating the whole food. See these resources about fruits and vegetables and how they may impact your overall health.
Focusing on single nutrients (in pill form) is not only expensive, it just doesn’t offer the promise that a balanced, varied diet can. Focus on food, instead. For more information about the benefits of food versus dietary supplements, check out this OPSS brochure, “Nutrition: Fueled for Fitness.”
Sports products and dietary supplements are often discussed on social media, but think twice before taking other’s word for it. A recent article in the British Medical Journal notes that claims and endorsements made on social media such as Facebook & Twitter are not regulated and may promote statements that have not been supported by science. Some red flags noted include:
- Paid endorsers. Do you know that some comments and images about a product can come from people (celebrities and non-celebrities) paid by companies to post great reviews about their products? Be careful that such claims may be coming from a paid sponsor and may exaggerate their results from a product.
- Endorsed hashtags. The hashtag such as “#ad” is a disclosure recommended by the Federal Trade Commission (FTC) to indicate that a social media post is coming from someone being paid (or otherwise reimbursed) by the company of the product they are endorsing. If such a hashtag appears in a social media post, then you know that it is sponsored and may be biased. (For more about FTC’s new endorsement guidelines, visit their FAQs web page.)
- Biased research. Assessing the science behind claims is the best way to evaluate a product. However, a common practice is that companies cite their own labs and research. When it comes to dietary supplements, it’s best to get information about products from unbiased, evidence-based organizations such as Natural Medicines Comprehensive Database, United States Pharmacopeias (USP), or NSF International.
- Unbalanced comments. When you scroll through a product’s social media page, do you find that all the reviews are positive? On platforms such as Facebook, companies have the ability to delete comments. A transparent company usually addresses negative comments and provides support to establish its position.
Look for these and other red flags when it comes to dietary supplements and their advertising. If you have a question about a particular sports product or dietary supplement and can’t find the answer on HPRC’s website, please use our “Ask The Expert” button located on the Operation Supplement Safety (OPSS) home page.