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Just published in The New England Journal of Medicine: A recent article brings up dietary supplement issues you need to be aware of and discusses how dietary supplement side effects could be monitored better. A PDF of the April 3rd article is available free online.

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You are here: Home / Dietary Supplements / Questions from the Field / The side effects of Apidexin

The side effects of Apidexin

Some of the notable side effects of the ingredients in Apidexin are headaches, insomnia, rapid heartbeat, raised blood pressure, nausea, vomiting, loose stools, diarrhea, belching, bloating, hiccups, and skin reactions. No data are available for the combination of ingredients.

From the Field

What do you know about the side effects of Apidexin?

HPRC’s Answer

Apidexin is a weight loss supplement; each capsule contains vitamin B12, chromax (a form of chromium), and proprietary blends of various ingredients.

According to the Natural Medicines Comprehensive Database’s evidence-based rating, Apidexin has a score of 4 on a scale of 1 (lowest rating) to 10 (highest rating) for overall safety, effectiveness, and product quality. Its rating is related to the effects of its known ingredients. One of the ingredients in Apidexin, guggul, is associated with side effects that include headaches, nausea, vomiting, loose stools, diarrhea, belching, bloating, hiccups, and skin reactions. Other ingredients in Apidexin also have known side effects. Irvingia gabonensis has been associated with headaches, flatulence, and difficulty sleeping. DiCaffeine Malate can cause jitters, insomnia, headaches, increased heart rate, and raised blood pressure. No data are available for the combination of the ingredients in Apidexin. However, there may be other ingredients in the proprietary blend that are not listed. We are checking with our partners to see if they have information on potential deviations from the label or the addition of other ingredients.

You can learn more on how to make informed decisions about dietary supplements and natural products from the Natural Medicines Comprehensive Database. We encourage consumers of dietary supplements only to consider using products rated 8 or above. These are in the green area of the scale and have evidence of safety. Items in the yellow range mean that data are lacking. The red area indicates there are well-known safety concerns or proven ineffectiveness. HPRC makes this user-friendly database readily available through links on its website for both Warfighters and healthcare professionals. Choose the appropriate version and follow the instructions to create an account.

You may also be interested in reading the article by the Food and Drug Administration titled "Tainted Weight Loss Products," which provides additional information about harmful products promoted for weight loss.